For Gnome and KDE users, the change of keyboard model/layout is easy and can be done without restarting X.

Simply go to:

Gnome Menu -> Applications -> Desktop Preferences -> Keyboard
KDE Menu -> Kontrol Center -> Accessibility -> Keyboard Layout

... and Logitech diNovo Media Desktop will appear in the list of keyboard models.

For other users, configuration of the xorg.conf might be the most convenient solution.
If this is what you want to do, modify your xorg.conf Keyboard Section to the following:

Replace the XkbLayout to the locale of choice.